View Pyruvate Kinase Deficiency Anemia Pics . Pyruvate kinase deficiency, one of the most common enzymatic defects of the erythrocyte, manifests clinically as a hemolytic anemia that can range from a mildly compensated anemia to severe anemia of childhood. It is the second most common rbc enzyme defect but is the commonest cause of chronic hemolytic anemia from an rbc enzyme deficiency. What is 'pyruvate kinase'? | A little biochem never hurt ... from shardakramharack.files.wordpress.com The pyruvate kinase test checks whether you have a pyruvate kinase deficiency, a genetic disorder that reduces the amount of red blood cells in your blood. Treatment of haemolytic anemia due to pyruvate kinase deficiency varies depending upon the severity of the disease. Pyruvate kinase deficiency is a condition a cat is born with, but symptoms do not usually arise until the cat reaches three years of age. ...